CD130 antibody
Catalogue Number: GTX109048-GTX
GTX109048 Image
GTX109048 Image
GTX109048 Image
GTX109048 Image
Various whole cell extracts (30 µg) were separated by 5% SDS-PAGE, and the membrane was blotted with CD130 antibody (GTX109048) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
GTX109048 Image
CD130 antibody detects CD130 protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. CD130 stained by CD130 antibody (GTX109048) diluted at 1:7500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
GTX109048 Image
Immunohistochemical analysis of paraffin-embedded J5 xenograft, using CD130(GTX109048) antibody at 1:500 dilution. Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min
| Manufacturer: | GeneTex |
| Preservative: | 0.025% ProClin 300|0.025% ProClin 300 |
| Molecular Weight: | 104 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | interleukin 6 signal transducer , CD130 , CDW130 , GP130 , IL-6RB |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 25 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant protein encompassing a sequence within the Intracellular domain of human CD130. The exact sequence is proprietary. |
| Application: | ICC, IF, IHC-P, WB |
Description
Description: The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
Additional Text
Uniprot ID
P40189
Gene ID
3572
Gene Name
IL6ST
Concentration
0.1 mg/ml
Purification
Affinity Purified
Molecular Weight
104
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX109048 Datasheet
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