PHD2 antibody
Catalogue Number: GTX10930-GTX
GTX10930 Image
GTX10930 Image
GTX10930 Image
GTX10930 Image
WB analysis of DDDDK-his-PHD1, PHD2, PHD3 recombinant protein, (10 ng/lane), hypoxia-treated HeLa and MEF cell lysate using GTX10930 PHD2 antibody.
GTX10930 Image
WB analysis of epitope-tagged PHD1, PHD2 or PHD3 (10 ng/lane) and hypoxia-treated HeLa cells lysate using GTX10930 PHD2 antibody. Dilution : 1 µg/ml
GTX10930 Image
FACS analysis of 10? Jurkat cells (fixed and permeabilized) in 150µl reaction using GTX10930 PHD2 antibody. Dilution : 3 µg/ml
| Manufacturer: | GeneTex |
| Preservative: | 0.09% sodium azide |
| Molecular Weight: | 46 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | egl-9 family hypoxia inducible factor 1 , C1orf12 , ECYT3 , HALAH , HIF-PH2 , HIFPH2 , HPH-2 , HPH2 , PHD2 , SM20 , ZMYND6 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide made to a C-terminal portion of human PHD2/HIF Prolyl Hydroxylase 2 (between amino acids 350-426) (GeneID 54583). |
| Application: | FC, ICC, IF, IHC-P, IP, EM, WB |
Description
Description: The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq]
Additional Text
Gene Name
EGLN1
Uniprot ID
Q9GZT9
Purification
Affinity Purified
Gene ID
54583
Molecular Weight
46
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Concentration
1 mg/ml
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.
Application Notes
WB: 1:500 - 1:2500. FCM: 1:10 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX10930 Datasheet
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