PLGF2 antibody [62526]

Catalogue Number: GTX10967-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:18
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:placental growth factor , AI854365 , PIGF , Plgf
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rat
Clone: 62526
Isotype: IgG2a
Immunogen: purified recombinant mouse placenta growth factor 2 expressed in insect Sf 21 cells.
Application: ELISA, WB, NT, Inh

Description

Description: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF, isolated from a human placental cDNA library, has 53% amino acid sequence homology in the PDGF-region of VEGF. As a result of alternative splicing, three human isoform precursors (PlGF1, PlGF2, and PlGF3) have been described. In mouse tissues, there is only one mRNA encoding the equivalent of human PlGF2.3 Mouse PlGF2 encodes a 158 amino acid precursor protein that shares a 65% homology with human PlGF2. The gene for PlGF is organized into seven exons and is mapped to chromosome 14. Placenta growth factor will potentiate VEGF that is present at low concentrations in vitro and in vivo. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.

Additional Text

Gene Name

PGF

Gene ID

18654

Uniprot ID

P49764

Purification

Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

18

Application Notes

WB: 1-2 µg/ml. ELISA: 0.5-1.0 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.