CD11c antibody [3.9]
Catalogue Number: GTX11029-GTX
| Manufacturer: | GeneTex |
| Preservative: | No preservative |
| Molecular Weight: | 128 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | CD11C,ITGAX,SLEB6,integrin subunit alpha X,CD11c,Integrin alpha X |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ug |
| Host name: | Mouse |
| Clone: | 3.9 |
| Isotype: | IgG1 |
| Immunogen: | Rheumatoid synovial fluid cells and fibronectin purified human monocytes |
| Application: | FC, ICC, IF, IHC-P, IP, WB, IHC-Fr, NT, Inh, InVivoA |
Description
Description: This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Additional Text
Gene Name
ITGAX
Gene ID
3687
Molecular Weight
128
Purification
Protein A/G Purified
Uniprot ID
P20702
Antibody Clonality
Monoclonal
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
WB: 1-10 µg/mL. FCM: ≤ 2 µg/10⁶ cells in a volume of 100 µL or 100µL of whole blood. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX11029 Datasheet
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