Caspase 3 antibody

Catalogue Number: GTX110543-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin™ 300
Molecular Weight:32
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:caspase 3 , CPP32 , CPP32B , SCA-1
Shipping Condition:Dry Ice
Unit(s): 100 ul, 25 ul, 10 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human Caspase 3. The exact sequence is proprietary.
Application: ICC, IF, IHC-P, IP, WB, IHC-Fr

Description

Description: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq]

Additional Text

Gene Name

CASP3

Gene ID

836

Uniprot ID

P42574

Concentration

0.8 mg/ml

Molecular Weight

32

Price
223.00


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