Myosin Light chain antibody [MY-21]
Catalogue Number: GTX11082-GTX
| Manufacturer: | GeneTex |
| Preservative: | 15 mM Sodium azide |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | myosin, light chain 1, alkali; skeletal, fast , MLC , MLC-1 , MLC-3 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | MY-21 |
| Isotype: | IgM |
| Immunogen: | chicken lens membrane. |
| Application: | ICC, IF, WB |
Description
Description: Contractile proteins are ubiquitous in eukaryotic cells. Their presence is related to motile functions. The two major cytoskeletal proteins implicated in cell motility are actin and myosin. Numerous investigators have shown that actin and myosin are constituents of many cell types and are involved in a myriad of cellular processes including locomotion, secretion, cytoplasmic streaming, phagocytosis, and cytokinesis. Myosin is a 500,000 dalton protein known to interact with identical heavy chains (200,000 daltons each) and four light chains (15,000-20,000 daltons). Myosin molecules consist of two major regions: tail (rod) and head regions. Myosin has three major biological functions:1. Myosin molecules spontaneously assemble into filaments in solutions of physiologic ionic strength and pH. Thick filaments consist mainly of myosin molecules.2. Myosin is an enzyme (ATPase) and its activity is the immediate source of the free energy that drives muscle contraction.3. Myosin binds to the polymerized form of actin, the major constituent of the thin filament.Myosin can be viewed in immunofluorescent microscopy enabling the delineation of the intracellular organization of proteins that are in the form of a supramolecular structure.
Additional Text
Gene Name
MYL1
Gene ID
396470
Purification
Unpurified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
ICC/IF: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Uniprot ID
P02604, P02605
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX11082 Datasheet
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