Vinculin antibody [VIN-11-5]

Catalogue Number: GTX11193-GTX

Manufacturer:	GeneTex
Preservative:	15 mM Sodium azide
Molecular Weight:	125
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	Vinculin
Shipping Condition:	Blue Ice
Unit(s):	200 ul
Host name:	Mouse
Clone:	VIN-11-5
Isotype:	IgG1
Immunogen:	smooth muscle vinculin from chicken gizzard.
Application:	ICC, IF, WB

Overview
Datasheets

Description

Description: Cytoskeletal filaments are associated with the plasma membrane in areas of cell contact. In particular it has been shown that bundles of actin containing microfilaments are attached to the cytoplasmic faces of the membrane in cell-substrate focal contacts (adhesion plaques) of cultured fibroblasts. Besides actin, which is the major constituent of microfilaments, other actin related proteins are found close to or in the area of microfilament membrane association in contact regions. Vinculin is associated with the cytoplasmic aspect of contact areas close to the membrane. It has been suggested that vinculin is a possible link between ends of the bundles of actin filaments and the plasma membrane. It has also been proposed that vinculin may be involved in the transmembrane induction of actin bundle formation.Monoclonal Anti-Vinculin may be used for the immunocytochemical localization of vinculin using indirect immunofluorescent labeling of cultured fibroblasts or for specific identification of the vinculin band in immunoblotting techniques.

Additional Text

Gene Name

VCL

Molecular Weight

125

Gene ID

396422

Purification

Unpurified

Uniprot ID

P12003

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

ICC/IF: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX11193 Datasheet

GTX11193 Reference

Price

£745.00

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