Kinesin antibody [IBII]

Catalogue Number: GTX11262-GTX

Manufacturer:GeneTex
Preservative:15 mM Sodium azide
Molecular Weight:75
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:kinesin family member 2A
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: IBII
Isotype: IgM
Immunogen: Bovine brain kinesin.
Application: ELISA, WB

Description

Description: Kinesin belongs to the group of motor proteins known to convert chemical energy released from ATP into mechanical energy. Conventional kinesin, member of the kinesin superfamily comprising more than 100 proteins, is involved in the anterograde vesicle transport inneuronal cells. Kinesin purified from mammalian brain homogenates is a heterotetramer consisting of two heavy (120 to 130 kDa) and two light chains (60 to 70 kDa), resulting in a molecular mass about 400 kDa. Each heavy chain contains an N-terminal globular motordomain with both a microtubule-binding site and an ATPase active center, stalk region responsible for heavy chain dimerization and finally C-terminal globular tail domain, which is implicated in cargo binding. Light chains may have a regulatory function.

Additional Text

Gene Name

KIF2A

Molecular Weight

75

Gene ID

768014

Purification

Unpurified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

UniProt ID

Q2NL05

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.