CD105 antibody [N1N3-2]

Catalogue Number: GTX112685-GTX

Manufacturer:GeneTex
Preservative:0.01% Thimerosal|0.01% Thimerosal
Molecular Weight:71
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:endoglin , END , HHT1 , ORW1
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the Extracellular domain of human CD105. The exact sequence is proprietary.
Application: IHC-P, WB

Description

Description: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Additional Text

Gene Name

ENG

Gene ID

2022

Purification

Affinity Purified

Molecular Weight

71

Uniprot ID

P17813

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.