PARP antibody [N2C1], Internal

Catalogue Number: GTX112864-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin™ 300
Molecular Weight:113
Physical state:Liquid
Type:ChIP Validated Antibodies
Alias:poly(ADP-ribose) polymerase 1 , ADPRT , ADPRT 1 , ADPRT1 , ARTD1 , PARP , PARP-1 , PPOL , pADPRT-1
Shipping Condition:Dry Ice
Unit(s): 100 ul, 25 ul, 10 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human PARP1. The exact sequence is proprietary.
Application: ICC, IF, IHC-P, IP, ChIP, WB

Description

Description: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

PARP1

Uniprot ID

P09874

Gene ID

142

Concentration

0.23 mg/ml

Molecular Weight

113

Protein Target Region

Internal

Price
223.00


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