TRADD antibody [N2C3]

Catalogue Number: GTX113042-GTX

Manufacturer:GeneTex
Preservative:0.01% Thimerosal
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:TNFRSF1A associated via death domain , Hs.89862
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human TRADD. The exact sequence is proprietary.
Application: IHC-P, WB

Description

Description: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq]

Additional Text

Gene ID

8717

Gene Name

TRADD

Uniprot ID

Q15628

Concentration

0.85 mg/ml

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

34

Application Notes

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.