CD41 antibody [N2C1], Internal

Catalogue Number: GTX113758-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin 300|0.025% ProClin 300
Molecular Weight:113
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:integrin subunit alpha 2b , BDPLT16 , BDPLT2 , CD41 , CD41B , GP2B , GPIIb , GT , GTA , HPA3 , PPP1R93
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the Extracellular domain of human CD41. The exact sequence is proprietary.
Application: ICC, IF, IHC-P, WB, IHC-Fr

Description

Description: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq]

Additional Text

Uniprot ID

P08514

Gene ID

3674

Gene Name

ITGA2B

Concentration

0.25 mg/ml

Purification

Affinity Purified

Molecular Weight

113

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.