Rapsyn antibody [1234]
Catalogue Number: GTX11423-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide|0.05% Sodium azide |
| Molecular Weight: | 46 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | receptor-associated protein of the synapse , 43kDa , Nraps , Raps , rapsyn |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Mouse |
| Clone: | 1234 |
| Isotype: | IgG1 |
| Immunogen: | Whole purified rapsyn from Torpedo californica electric organ postsynaptic membrane. |
| Application: | ICC, IF, WB, IHC-Fr |
Description
Description: Nicotinic acetylcholine receptors (AChRs) are organized into high-density postsynaptic clusters at the motor endplate that are critical for efficient synaptic transmission. The organization of AChR's is carried out by the 43 kDa cytoplasmic protein rapsyn. Studies have indicated that mutations which impair the activity of rapsyn can lead to the formation of congenital myasthenic syndrome (CMS). CMS is characterized by poor development of the postsynaptic region.
Additional Text
Gene Name
RAPSN
Purification
Protein G purified
Molecular Weight
46
Gene ID
19400
Uniprot ID
P12672
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Concentration
1 mg/ml
Application Notes
WB: 0.5 µg/ml. ICC/IF: 2 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX11423 Datasheet
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