Osteopontin antibody
Catalogue Number: GTX11503-GTX
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Molecular Weight: | 32 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | secreted phosphoprotein 1 , 2AR , Apl-1 , BNSP , BSPI , Bsp , ETA-1 , Eta , OP , Opn , Opnl , Ric , Spp-1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | purified recombinant mouse osteopontin expressed in NSO cells. |
| Application: | ELISA, WB, IHC, NT, Inh |
Description
Description: Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. OPN is multifunctional, with activities in cell migration, cell survival, inhibition of calcification, regulation of immune cell function, and control of tumor cell phenotype. Targeting of the gene encoding Osteopontin, has revealed that while it is not necessary for normal embryonic development, fertility, and health under pathogen-free conditions, loss of the protein has significant consequences in several models of injury/disease as diverse as renal injury, viral and bacterial infection, bone remodeling, and tumor growth. The fact that no other proteins seem to share a redundant activity with Osteopontin under these conditions suggests that it has a unique functional role during tissue injury and stress.
Additional Text
Gene Name
SPP1
Uniprot ID
P10923
Molecular Weight
32
Purification
Affinity Purified
Gene ID
20750
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
WB: 0.1-0.2 µg/ml. ELISA: 0.2-0.8 µg/ml. IHC: 5-15 µg/ml. Neutralizing/Inhibition: 1-3 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX11503 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations