alpha Fodrin antibody [D8B7]
Catalogue Number: GTX11755-GTX
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Molecular Weight: | 285 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | spectrin alpha, non-erythrocytic 1 , EIEE5 , NEAS , SPTA2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | D8B7 |
| Isotype: | IgG2b |
| Immunogen: | Recombinant alpha II spectrin (non-erythroid spectrin or fodrin) SH3 domain (Human). |
| Application: | ELISA, ICC, IF, WB, IHC-Fr |
Description
Description: Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]
Additional Text
Gene ID
6709
Gene Name
SPTAN1
Uniprot ID
Q13813
Molecular Weight
285
Purification
Unpurified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
ELISA: Use at a dilution of 1/10^5-1/10^6IF: Use at a dilution of 1/100 - 1/500. IHC-Fr: Use at a dilution of 1/50 - 1/100. WB: Use at a dilution of 1/10^2-1/10^3. Predicted molecular weight: 297 kDa. Optimal dilutions/concentrations should be determined by the end user.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX11755 Datasheet
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