DR4 antibody [32A1380]

Catalogue Number: GTX11931-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:50
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:TNF receptor superfamily member 10a , APO2 , CD261 , DR4 , TRAILR-1 , TRAILR1
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Mouse
Clone: 32A1380
Isotype: IgG1
Immunogen: This monoclonal antibody was raised against a peptide corresponding to amino acid 2 to 21 of human DR4.
Application: FC, ICC, IF, WB, MS

Description

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq]

Additional Text

Gene Name

TNFRSF10A

Gene ID

8797

Uniprot ID

O00220

Purification

Protein G purified

Molecular Weight

50

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 2 - 4 µg/ml. FCM: 1:20 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.