TLR8 antibody [44C143]
Catalogue Number: GTX12120-GTX
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FACS analysis of mouse splenocytes using GTX12120 TLR8 antibody [44C143]. Red : primary antibody Green : isotype control Antibody amount : 2µg
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IHC-P analysis of human spleen tissue using GTX12120 TLR8 antibody [44C143]. Dilution : 2 µg/ml
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FACS (Intracellular staining) analysis of (A) A549 cells (B) 293T cells(as negative control) using GTX12120 TLR8 antibody [44C143]. Blue : Primary antibody Orange : isotype control Dilution : 5 µg/ml Fixation : 4% PFA Permibilization : 0.1% saponin
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FACS (Intracellular staining) analysis of human lymphocytes using GTX12120 TLR8 antibody [44C143]. Red : Primary antibody Green : isotype control Shaded histogram : cell only
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FACS (Intracellular staining) analysis of Ramos cells using GTX12120 TLR8 antibody [44C143]. Red : Primary antibody Green : isotype control Shaded histogram : cell only Antibody amount : 2 µg
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WB analysis of Ramos (left) and human spleen (right) lysate using GTX12120 TLR8 antibody [44C143].
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WB analysis of Ramos cell lysate using GTX12120 TLR8 antibody [44C143].
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FACS analysis of 10? human lymphocytes using GTX12120 TLR8 antibody [44C143]. Red : Primary antibody Green : isotype control Shaded histogram : cell only Antibody amount : 1 µg
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide|0.05% Sodium azide |
| Molecular Weight: | 120 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | toll like receptor 8 , CD288 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Mouse |
| Clone: | 44C143 |
| Isotype: | IgG1 |
| Immunogen: | This antibody was developed against a KLH-conjugated synthetic peptide of human TLR8, within amino acids 750-850. |
| Application: | FC, IHC-P, WB, MS |
Description
Description: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq]
Additional Text
Gene Name
TLR8
Gene ID
51311
Purification
Protein G purified
Molecular Weight
120
Uniprot ID
Q9NR97
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Concentration
1 mg/ml
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
WB: 1 - 3 µg/ml. IHC-P: 5 µg/ml. FCM: 0.5 - 1 µg / 10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX12120 Datasheet
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