HIF1 alpha antibody

Catalogue Number: GTX127309-GTX

Manufacturer:	GeneTex
Preservative:	0.025% ProClin 300
Physical state:	Liquid
Type:	ChIP Validated Antibodies
Alias:	hypoxia inducible factor 1 subunit alpha , HIF-1-alpha , HIF-1A , HIF-1alpha , HIF1 , HIF1-ALPHA , MOP1 , PASD8 , bHLHe78
Shipping Condition:	Blue Ice
Unit(s):	100 ul, 25 ul
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Recombinant protein encompassing a sequence within the C-terminus region of human HIF1 alpha. The exact sequence is proprietary.
Application:	ICC, IF, IHC-P, IP, ChIP, WB, IHC-Fr

Overview
Datasheets

Description

Description: Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]

Additional Text

Gene Name

HIF1A

Gene ID

3091

Uniprot ID

Q16665

Purification

Affinity Purified

Molecular Weight

Concentration

1.46 mg/ml

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:570. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Short Description

HIF1 alpha antibody recognizes HIF1 alpha (HIF1a) protein, which is a subunit of the heterodimeric transcription factor hypoxia-inducible factor-1 (HIF-1). HIF-1 is a master regulator of homeostatic adaption to hypoxia (low oxygen supply) in various physiological and pathological conditions including normal development and cancer.

GTX127309 Datasheet

GTX127309 Reference

Price

£285.00

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