Twist1/2 antibody
Catalogue Number: GTX127310-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.025% ProClin 300 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 25 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant protein encompassing a sequence within the center region of human Twist1/2. The exact sequence is proprietary. |
| Application: | IHC-P, WB, IHC |
Description
Description: This gene encodes a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. The encoded protein forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. This protein may also regulate neural tube closure, limb development and brown fat metabolism. This gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis. Mutations in this gene cause Saethre-Chotzen syndrome in human patients, which is characterized by craniosynostosis, ptosis and hypertelorism. [provided by RefSeq, Aug 2017]
Additional Text
Gene Name
TWIST1
Gene ID
7291
Concentration
0.67 mg/ml
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
21
Application Notes
WB: 1:500-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Specificity
ACS3 antibody , B-HLH DNA binding protein antibody , BPES2 antibody , BPES3 antibody , CRS1 antibody , DERMO1 antibody , H-twist antibody , MGC117334 antibody , SCS antibody , TWIST antibody , TWIST homolog of drosophila antibody , TWIST1 antibody , TWIST2 antibody , bHLHa38 antibody , bHLHa39 antibody , class A basic helix-loop-helix protein 38 antibody , class A basic helix-loop-helix protein 39 antibody , dermis-expressed protein 1 antibody , twist homolog 2 (Drosophila) antibody , twist-related bHLH protein Dermo1 antibody , twist-related protein 1 antibody , twist-related protein 2 antibody
GTX127310 Datasheet
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