LC3B antibody
Catalogue Number: GTX127375-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.025% ProClin 300 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | microtubule associated protein 1 light chain 3 beta , ATG8F , LC3B , MAP1A/1BLC3 , MAP1LC3B-a |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 25 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human LC3B. The exact sequence is proprietary. |
| Application: | FACS, ICC, IF, IHC-P, IP, WB, IHC-Fr |
Description
Description: The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq]
Additional Text
Gene Name
MAP1LC3B
Uniprot ID
Q9GZQ8
Concentration
0.32 mg/ml
Gene ID
81631
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
15
Application Notes
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Short Description
LC3B antibody recognizes LC3B, an autophagosomal membrane structural protein with a predicted molecular weight of 14.7 kDa. LC3B protein is a member of the highly conserved Atg8 protein family, which encompasses the LC3 and GABARAP subfamilies. The key function of LC3B involves autophagy substrate selection during autophagosome formation. Therefore, LC3B antibody is of great utility for the study of autophagosome biogenesis.
GTX127375 Datasheet
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