RANTES antibody (Biotin)

Catalogue Number: GTX12766-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:10
Physical state:Liquid
Type:Polyclonal Primary Antibody - Conjugated
Alias:C-C motif chemokine ligand 5 , D17S136E , RANTES , SCYA5 , SIS-delta , SISd , TCP228 , eoCP
Shipping Condition:Blue Ice
Unit(s): 25 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hRANTES (human RANTES).
Application: ELISA, sELISA, WB

Description

Description: RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV-suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). It is T-cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.

Additional Text

Gene ID

6352

Gene Name

CCL5

Uniprot ID

P13501

Molecular Weight

10

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 0.1 - 0.2 µg/mL. ELISA: 0.15 - 0.30 ng/mL. Sandwich ELISA: 0.25 - 1.0 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.