Catalogue Number: GTX129120-GTX
Manufacturer: | GeneTex |
Preservative: | 0.01% Thimerosal |
Physical state: | Liquid |
Type: | Polyclonal Primary Antibody - Unconjugated |
Alias: | Activating transcription factor 3 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul, 25 ul |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | Full length human ATF3 Recombinant protein. |
Application: | ICC, IF, WB |
Description: Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. [provided by RefSeq]
1 mg/ml
467
ATF3
P18847
Affinity Purified
Polyclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
21
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.