IL1 beta antibody

Catalogue Number: GTX130021-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin™ 300
Molecular Weight:31
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:interleukin 1 beta , IL-1 , IL1-BETA , IL1F2
Shipping Condition:Dry Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human IL1 beta. The exact sequence is proprietary.
Application: ICC, IF, WB

Description

Description: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq]

Additional Text

Gene Name

IL1B

Gene ID

3553

Uniprot ID

P01584

Concentration

1.2 mg/mL

Molecular Weight

31

Price
223.00


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