AMPK alpha 1 (phospho Thr183) + AMPK alpha 2 (phospho Thr172) antibody

Catalogue Number: GTX130429-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin 300
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:protein kinase AMP-activated catalytic subunit alpha 1 , AMPK , AMPKa1
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Thr183 of human AMPK alpha 1. The exact sequence is proprietary.
Application: WB

Description

Description: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]

Additional Text

Gene ID

5562

Uniprot ID

Q13131

Gene Name

Prkaa1

Concentration

1.5 mg/ml

Purification

Affinity Purified

Modification

Phosphorylated, Thr172

Molecular Weight

64

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.