TCEB1 antibody

Catalogue Number: GTX132302-GTX

Manufacturer:GeneTex
Preservative:no preservative|No Preservative
Molecular Weight:12
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:elongin C , SIII , TCEB1
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human TCEB1. The exact sequence is proprietary.
Application: WB

Description

Description: This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq]

Additional Text

Concentration

0.5 mg/ml

Uniprot ID

Q15369

Purification

Affinity Purified

Gene ID

6921

Gene Name

ELOC

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

12

Application Notes

WB: 1:1000-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.