alpha Synuclein antibody

Catalogue Number: GTX133367-GTX

Manufacturer:GeneTex
Preservative:no preservative|0.025% ProClin 300
Molecular Weight:14
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:synuclein alpha , NACP , PARK1 , PARK4 , PD1
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human alpha Synuclein. The exact sequence is proprietary.
Application: IHC-P, WB, IHC-Fr

Description

Description: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq]

Additional Text

Concentration

1 mg/ml

Gene ID

6622

Gene Name

SNCA

Uniprot ID

P37840

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

14

Application Notes

WB: 1:500-1:3000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Price
£276.00


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