ULK1 (phospho Ser638) antibody

Catalogue Number: GTX133540-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin 300
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:unc-51 like autophagy activating kinase 1 , ATG1 , ATG1A , UNC51 , Unc51.1 , hATG1
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Ser638 of human ULK1. The exact sequence is proprietary.
Application: WB

Description

Description: Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells.

Additional Text

Uniprot ID

O75385

Gene Name

ULK1

Purification

Affinity Purified

Gene ID

8408

Molecular Weight

113

Concentration

1.48 mg/ml

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Modification

Phosphorylated, Ser638

Application Notes

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.