PDGF Receptor alpha antibody

Catalogue Number: GTX133588-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin 300|0.025% ProClin 300
Molecular Weight:123
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:platelet derived growth factor receptor alpha , CD140A , PDGFR-2 , PDGFR2
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthetic peptide encompassing a sequence within the Intracellular domain of human PDGF Receptor alpha. The exact sequence is proprietary.
Application: WB

Description

Description: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq]

Additional Text

Gene Name

PDGFRA

Uniprot ID

P16234

Gene ID

5156

Concentration

1.21 mg/ml

Purification

Affinity Purified

Molecular Weight

123

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.