NFkB p65 (phospho Ser536) antibody

Catalogue Number: GTX133899-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin 300
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:RELA proto-oncogene, NF-kB subunit , CMCU , NFKB3 , p65
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Ser536 of human NFkB p65. The exact sequence is proprietary.
Application: ICC, IF, WB

Description

Description: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Additional Text

Gene Name

RELA

Gene ID

5970

Uniprot ID

Q04206

Concentration

0.59 mg/ml

Purification

Affinity Purified

Modification

Phosphorylated, Ser536

Molecular Weight

60

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.