TGF beta Receptor I antibody

Catalogue Number: GTX134209-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin 300
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:transforming growth factor beta receptor 1 , AAT5 , ACVRLK4 , ALK-5 , ALK5 , ESS1 , LDS1 , LDS1A , LDS2A , MSSE , SKR4 , TBR-i , TBRI , TGFR-1 , tbetaR-I
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human TGF beta Receptor I. The exact sequence is proprietary.
Application: WB

Description

Description: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Additional Text

Gene Name

TGFBR1

Uniprot ID

P36897

Gene ID

7046

Concentration

2.39 mg/mL

Purification

Affinity Purified

Molecular Weight

56

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.