IGF1R antibody

Catalogue Number: GTX134417-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin 300
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:insulin like growth factor 1 receptor , CD221 , IGFIR , IGFR , JTK13
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human IGF1R. The exact sequence is proprietary.
Application: WB

Description

Description: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Additional Text

Gene Name

IGF1R

Gene ID

3480

Uniprot ID

P08069

Concentration

0.7 mg/ml

Purification

Affinity Purified

Molecular Weight

155

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.