CENPA antibody

Catalogue Number: GTX134430-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin 300
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:centromere protein A , CENP-A , CenH3
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CENPA. The exact sequence is proprietary.
Application: IHC-P, WB

Description

Description: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015]

Additional Text

Gene Name

CENPA

Gene ID

1058

Uniprot ID

P49450

Purification

Affinity Purified

Concentration

1.11 mg/ml

Antibody Clonality

Polyclonal

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Molecular Weight

16

Application Notes

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.