beta Amyloid (1-42) antibody - Conformation Specific

Catalogue Number: GTX134510-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin™ 300
Molecular Weight:87
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:amyloid beta precursor protein , AAA , ABETA , ABPP , AD1 , APPI , CTFgamma , CVAP , PN-II , PN2 , preA4
Shipping Condition:Dry Ice
Unit(s): 100 ul, 25 ul, 10 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen:
Application: ELISA, IHC-P, DB

Description

Description: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]

Additional Text

Gene Name

APP

Gene ID

351

Uniprot ID

P05067

Concentration

0.45 mg/ml

Molecular Weight

87

Price
223.00


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