Caspase 4 antibody

Catalogue Number: GTX134552-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin™ 300
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:caspase 4 , ICE(rel)II , ICEREL-II , ICH-2 , Mih1 , Mih1/TX , TX
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Caspase 4. The exact sequence is proprietary.
Application: IHC-P, WB

Description

Description: This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

CASP4

Uniprot ID

P49662

Gene ID

837

Concentration

2.51 mg/ml

Antibody Clonality

Polyclonal

Application Notes

WB: 1:500-1:3000. IHC-P: Assay dependent. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Price
223.00


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