Claudin 1 antibody

Catalogue Number: GTX134842-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin 300
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:claudin 1 , CLD1 , ILVASC , SEMP1
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Claudin 1. The exact sequence is proprietary.
Application: ICC, IF, WB

Description

Description: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

9076

Gene Name

CLDN1

Uniprot ID

O95832

Concentration

0.43 mg/ml

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Molecular Weight

23

Application Notes

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.