TRF2 antibody [4A794.15]

Catalogue Number: GTX13579-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:60
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:telomeric repeat binding factor 2 , TRBF2 , TRF2
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 4A794.15
Isotype: IgG1
Immunogen: Baculovirus expressed whole length TRF2 protein was used for immunizing mice and splenocytes used to generate the hybridoma clone (NP_005643).
Application: ELISA, FC, ICC, IF, IHC-P, IP, ChIP, WB, IHC-Fr, PLA, MS

Description

Description: This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. [provided by RefSeq]

Additional Text

Gene Name

TERF2

Gene ID

7014

Purification

Protein G purified

Molecular Weight

60

Uniprot ID

Q15554

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 2 - 4 µg/ml. ICC/IF: 1:10 - 1:500. IHC-Fr: 5 µg/ml. FCM: 0.1 µg / 10⁶ cells. IP: 2 µg/ 10⁶ cells. ELISA: 2 µg/ml. ChIP assay: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.