sRANKL antibody [12A668]

Catalogue Number: GTX13582-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:35
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:tumor necrosis factor (ligand) superfamily, member 11 , Ly109l , ODF , OPGL , RANKL , Trance
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 12A668
Isotype: IgG1
Immunogen: A bacterially expressed fusion protein containing amino acid residues 1-317 of mouse TRANCE was used as immunogen.
Application: FC, ICC, IF, IHC-P, ChIP, WB

Description

Description: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.

Additional Text

Uniprot ID

O35235

Gene Name

TNFSF11

Gene ID

21943

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

35

Concentration

1 mg/ml

Application Notes

WB: 0.5 - 2 µg/ml. IHC-P: 5 µg/ml. ChIP assay: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.