Human IL6 protein, His tag

Catalogue Number: GTX135982-PRO-GTX

Manufacturer:GeneTex
Preservative:no preservative|No Preservative
Physical state:Liquid
Type:Interleukins
Alias:interleukin 6 , BSF-2 , BSF2 , CDF , HGF , HSF , IFN-beta-2 , IFNB2 , IL-6
Host Cell:HEK293 cells
Shipping Condition:Dry Ice
Unit(s): 100 ug
Application: ELISA, sELISA

Description

Description: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Additional Text

Gene Name

IL6

Gene ID

3569

Uniprot ID

P05231

Protein Tag

HIS Tag

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

Recommended antibody pairs for sandwich ELISA: Capture : GTX636571 / GTX636573, Detection : GTX636473 / GTX638598.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. For long-term storage after reconstitution, aliquot and store at -70C or below. Do not vortex.