HFE antibody

Catalogue Number: GTX135988-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin 300
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:homeostatic iron regulator , HFE1 , HH , HLA-H , MVCD7 , TFQTL2
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human HFE. The exact sequence is proprietary.
Application: WB

Description

Description: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

HFE

Uniprot ID

Q30201

Gene ID

3077

Purification

Affinity Purified

Concentration

1.64 mg/ml

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

40

Application Notes

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.