SIRT1 antibody

Catalogue Number: GTX13749-GTX

Manufacturer:GeneTex
Preservative:0.1% Sodium azide
Molecular Weight:82
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:sirtuin 1 , SIR2 , SIR2L1 , SIR2alpha
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Peptide mapping to the carboxy terminal domain of human SIRT1.
Application: IP, ChIP, WB

Description

Description: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

Additional Text

Gene ID

23411

Gene Name

SIRT1

Uniprot ID

Q96EB6

Concentration

0.2 mg/ml

Purification

Affinity Purified

Molecular Weight

82

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.