Human GM-CSF protein (active)
Catalogue Number: GTX137974-PRO-GTX
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GTX137974-PRO Image
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GTX137974-PRO Image
GTX137974-PRO Image
Serial dilutions of Human GM-CSF protein (active) were added to TF-1 cells. Cell proliferation was measured and the linear portion of the curve was used to calculate the ED50. *This product has been tested against the competitor and the biological activity is better than competitor.
GTX137974-PRO Image
1µg of GTX137974-pro Human GM-CSF protein (active) was analyzed using SDS-PAGE and stained with coomassie blue and captured by monochrome camera.
| Manufacturer: | GeneTex |
| Preservative: | No preservative |
| Physical state: | Lyophilized |
| Type: | Growth Factors |
| Alias: | colony stimulating factor 2 , CSF , GMCSF |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Application: | FA |
Description
Description: The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]
Additional Text
Gene Name
CSF2
Gene ID
1437
Accession Number
NP_000749.2
Uniprot ID
P04141
Application Notes
The ED₅₀ was determined by a cell proliferation assay using TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
Short Description
GM-CSF, a colony stimulating factor also known as CSF2, mediates the proliferation, differentiation, and functions of hematopoietic precursor cells. This bioactive recombinant human GM-CSF is a 14.6 kDa globular protein formed by a 128 a.a. polypeptide with two intramolecular disulfide bonds and two potential N-linked glycosylation sites.
Storage Note
Store at 4C or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. For long-term storage after reconstitution, aliquot and store at -70C or below. Do not vortex.
GTX137974-PRO Datasheet
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