RPE65 antibody [401.8B11.3D9]

Catalogue Number: GTX13826-GTX

Manufacturer:	GeneTex
Preservative:	0.05% Sodium azide\|0.05% Sodium azide
Molecular Weight:	61
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	retinoid isomerohydrolase RPE65
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	401.8B11.3D9
Isotype:	IgG1
Immunogen:	Bovine RPE65 microsomal membrane proteins. [UniProt# Q28175]
Application:	FC, ICC, IF, IHC-P, WB, IHC-Fr, MS

Overview
Datasheets

Description

Description: Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.

Additional Text

Gene Name

RPE65

Purification

Protein G purified

Molecular Weight

Gene ID

282043

Uniprot ID

Q28175

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

WB: 1:500 - 1:1000. ICC/IF: 1:10 - 1:500. IHC-P: 1:250 - 1:500. IHC-Fr: 1:250. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX13826 Datasheet

GTX13826 Reference

Price

£422.00

-

Quantity
Unit Size

Find out about delivery