PMS2 antibody [163C1251]

Catalogue Number: GTX13900-GTX

Manufacturer:	GeneTex
Preservative:	0.05% Sodium azide\|0.05% Sodium azide
Molecular Weight:	96
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	PMS1 homolog 2, mismatch repair system component , HNPCC4 , MLH4 , PMS2CL , PMSL2
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	163C1251
Isotype:	IgG1
Immunogen:	This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 623-639 SSLAKRIKQLHHEAQQS of human PMS2; GenBank No. NP_000526.1.
Application:	FC, IHC-P, WB, MS

Overview
Datasheets

Description

Description: This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq]

Additional Text

Gene Name

PMS2

Gene ID

5395

Uniprot ID

P54278

Purification

Protein G purified

Molecular Weight

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 1 - 2 µg/ml. IHC-P: 2 - 5µg/ml. FCM: 1µg / 10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX13900 Datasheet

Price

£410.00

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Quantity
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