Lamin A + C antibody

Catalogue Number: GTX13910-GTX

Manufacturer:	GeneTex
Preservative:	0.05% Sodium azide
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	lamin A/C , CDCD1 , CDDC , CMD1A , CMT2B1 , EMD2 , FPL , FPLD , FPLD2 , HGPS , IDC , LDP1 , LFP , LGMD1B , LMN1 , LMNC , LMNL1 , MADA , PRO1
Shipping Condition:	Blue Ice
Unit(s):	200 ul
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	A synthetic peptide corresponding to amino acids 249-265 CRAQHEDQVEQYKKELEK of Human Lamin A/C was used immunogen.
Application:	FACS, ICC, IF, WB

Overview
Datasheets

Description

Description: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq]

Additional Text

Gene Name

LMNA

Gene ID

4000

Uniprot ID

P02545

Molecular Weight

Purification

Unpurified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500 - 1:1000. ICC/IF: 1:100. FACS: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX13910 Datasheet

Price

£351.00

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