Estrogen Receptor alpha antibody

Catalogue Number: GTX14020-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:66
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:estrogen receptor 1 , ER , ESR , ESRA , ESTRR , Era , NR3A1
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Chicken
Clone:
Isotype: IgY
Immunogen: Immunogen Sequence: GI # 4503603, sequence 255-367 Recombinant estrogen receptor 1
Application: WB

Description

Description: This antibody recognizes human ER-alpha, a 65 kD protein and a member of the steroid family of nuclear receptors. ER-alpha is a ligand-activated transcription factor that, when bound to estrogen, induces a conformational change that allows dimerization and binding to estrogen response element sequences. When bound to DNA, ER-alpha can positively or negatively regulate gene transcription.

Additional Text

Gene ID

2099

Gene Name

ESR1

Uniprot ID

P03372

Purification

Affinity Purified

Molecular Weight

66

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.