IL21 antibody

Catalogue Number: GTX14037-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:17
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:interleukin 21 , IL-21
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Chicken
Clone:
Isotype: IgY
Immunogen: Immunogen Sequence: GI # 11140821, sequence 18-146 Recombinant interleukin 21 [Mus musculus]
Application: ELISA, WB

Description

Description: A novel cytokine related to IL2 and IL15 was recently identified and designated IL21. The receptor for IL21 (IL21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL21 signaling. Both IL21R and the gc are necessary for the IL21 function. IL21 and its receptor activate JAKSTAT signaling pathway. IL21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL21 plays a role in the proliferation and maturation of NK, B and T cell populations.

Additional Text

Gene ID

60505

Gene Name

IL21

Uniprot ID

Q9ES17

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

17

Application Notes

WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.