LDL receptor antibody

Catalogue Number: GTX14056-GTX

Manufacturer:	GeneTex
Preservative:	0.02% Sodium azide\|0.02% Sodium azide
Molecular Weight:	95
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	low density lipoprotein receptor , FH , FHC , LDLCQ2
Shipping Condition:	Blue Ice
Unit(s):	50 ug
Host name:	Chicken
Clone:
Isotype:	IgY
Immunogen:	Immunogen Sequence: GI # 4504975, sequence 29-205 Recombinant low density lipoprotein receptor
Application:	WB

Overview
Datasheets

Description

Description: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia.

Additional Text

Gene Name

LDLR

Uniprot ID

P01130

Gene ID

3949

Purification

Affinity Purified

Molecular Weight

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX14056 Datasheet

Price

£537.00

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Quantity
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