Catalogue Number: GTX14097-GTX
Manufacturer: | GeneTex |
Preservative: | No preservative |
Physical state: | Liquid |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | TBET,TBLYM,TBX21,TPET,Tbet,Tbox 21,T-bet,T bet,T-box transcription factor 21 |
Shipping Condition: | Blue Ice |
Unit(s): | 500 ug |
Host name: | Mouse |
Clone: | 4B10 |
Isotype: | IgG1 |
Immunogen: | |
Application: | FACS, IHC-P, IP, WB |
Description: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008]
TBX21
Q9UL17
30009
Protein G purified
58
Monoclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption