TBX21 antibody [4B10]

Catalogue Number: GTX14097-GTX

Manufacturer:GeneTex
Preservative:No preservative
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:TBET,TBLYM,TBX21,TPET,Tbet,Tbox 21,T-bet,T bet,T-box transcription factor 21
Shipping Condition:Blue Ice
Unit(s): 500 ug
Host name: Mouse
Clone: 4B10
Isotype: IgG1
Immunogen:
Application: FACS, IHC-P, IP, WB

Description

Description: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

TBX21

Uniprot ID

Q9UL17

Gene ID

30009

Purification

Protein G purified

Molecular Weight

58

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption