C3 antibody

Catalogue Number: GTX14232-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:187
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:complement C3 , AHUS5 , ARMD9 , ASP , C3a , C3b , CPAMD1 , HEL-S-62p
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Chicken
Clone:
Isotype: IgY
Immunogen: Complement C3 native protein. Immunogen Sequence: GI # 4557385, sequence 1-1663
Application: ELISA, ICC, IF, WB, IHC

Description

Description: The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a andC3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.

Additional Text

Gene Name

C3

Uniprot ID

P01024

Gene ID

718

Purification

Affinity Purified

Molecular Weight

187

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.