TANK antibody

Catalogue Number: GTX14272-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:48
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:TRAF family member associated NFKB activator , I-TRAF , ITRAF , TRAF2
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Chicken
Clone:
Isotype: IgY
Immunogen: Immunogen Sequence: GI # 19743571, sequence 1-110 Recombinant TRAF interacting protein TANK isoform b
Application: WB

Description

Description: The TRAF (tumor necrosis factor receptor associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, this protein can block TRAF2 binding to LMP1, the Epstein Barr virus transforming protein, and inhibit LMP1-mediated NF kappa B activation.

Additional Text

Gene ID

10010

Gene Name

TANK

Uniprot ID

Q92844

Purification

Affinity Purified

Molecular Weight

48

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.